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UID:1775@azbio.org
DTSTART;TZID=America/Phoenix:20221213T090000
DTEND;TZID=America/Phoenix:20221213T100000
DTSTAMP:20221209T161131Z
URL:https://www.azbio.org/events/htg-therapeutics-key-opinion-leader-kol-w
 ebinar-the-role-of-rna-profiling-in-drug-discovery-and-analysis
SUMMARY:HTG Therapeutics key opinion leader (KOL) webinar: “The Role of R
 NA Profiling in Drug Discovery and Analysis” -  - 13 Dec 22 09:00
DESCRIPTION:\n\nTUCSON\, Ariz.\, Dec. 09\, 2022 (GLOBE NEWSWIRE) -- HTG Mol
 ecular Diagnostics\, Inc. (Nasdaq: HTGM) (HTG)\, a life science company ad
 vancing precision medicine through its innovative transcriptome-wide profi
 ling and advanced medicinal chemistry technology\, today announced it will
  host its next HTG Therapeutics key opinion leader (KOL) webinar: “The R
 ole of RNA Profiling in Drug Discovery and Analysis”\, on Tuesday\, Dece
 mber 13\, 2022 at 11:00 am Eastern Standard Time.\n\nThis latest webinar f
 eatures a presentation from KOL\, Dr. Robert Spitale\, PhD\, from the Univ
 ersity of California - Irvine\, discussing the use of RNA profiling in the
  drug discovery process to better uncover mechanism of action and refine t
 he drug screening processes.\n\nAdditionally\, the HTG Therapeutics team w
 ill present results from the application of its transcriptome-informed dru
 g discovery process. Specifically\, differential regulation of the ferropt
 osis pathway by structurally similar compounds that target mTOR will be of
 fered as an example of how RNA profiling can aid in understanding post-tar
 get engagement consequences and expand our understanding of the biological
  implications of compound treatment.  \n\nHTG Therapeutics\, the company
 ’s drug discovery business unit\, is actively using its transcriptome-in
 formed approach to drug discovery to design and further refine small-molec
 ule chemical libraries. The goal of this approach is to enable the selecti
 on and characterization of de-risked candidate molecules across selected t
 herapeutic targets of interest leading to potential business development a
 nd licensing opportunities in various therapeutic areas. A video providing
  an overview of HTG’s Therapeutics business and a link to the replay of 
 initial presentation in this KOL series are available on the Company’s w
 ebsite HERE.\n\nA live question and answer session will follow the present
 ations. Please register for the event HERE.\n\nAbout KOL Dr. Spitale:\n\nD
 r. Spitale currently serves as the Associate Director and Associate Dean o
 f Research in the School of Pharmacy &amp\; Pharmaceutical Sciences at Uni
 versity of California\, Irvine (UCI). After joining UCI Pharmaceutical Sci
 ences Department as an Assistant Professor in 2014\, he was promoted to As
 sociate Professor in 2018\, and rose to the ranks of Professor in 2020. In
  this time\, Dr. Spitale’s research has focused on developing novel chem
 ical and bioinformatic approaches toward understanding the role of RNA str
 ucture and function in normal biology as well as disease. Beyond his resea
 rch accomplishments\, he has been an active presence in the UCI community 
 as the Director of the RNA Club and its annual symposium\, a co-founder of
  the Chemical and Systems Biology Club and the faculty advisor for the Pha
 rm Sci undergraduate student council. He is also a vital part of the devel
 opment of the planned School of Pharmacy and Pharmaceutical Sciences\, hav
 ing served on the Pharmacy Planning group responsible for creating proposa
 ls to the UCI Senate\, UC System\, and the Accreditation Council for Pharm
 acy Education (ACPE). Dr. Spitale received his Ph.D. degree in Chemistry a
 t the University of Rochester in 2009\, as an Elon Huntington Hooker Fello
 w with Professor Joseph Wedekind. He then transitioned to postdoctoral stu
 dies at Stanford University and was awarded the A.P. Giannini Fellowship t
 o support his research with Professor Howard Chang.\n\nAbout HTG: \n\nHTG 
 is accelerating precision medicine from diagnosis to treatment by harnessi
 ng the power of transcriptome-wide profiling to drive translational resear
 ch\, novel therapeutics and clinical diagnostics across a variety of disea
 se areas.\n\nBuilding on more than a decade of pioneering innovation and p
 artnerships with biopharma leaders and major academic institutes\, HTG’s
  proprietary RNA platform technologies are designed to make the developmen
 t of life science tools and diagnostics more effective and efficient and t
 o unlock a differentiated and disruptive approach to transformative drug d
 iscovery. For more information visit www.htgmolecular.com.\n\nForward-Look
 ing Statements:\n\nStatements contained in this press release regarding ma
 tters that are not historical facts are “forward-looking statements” w
 ithin the meaning of the Private Securities Litigation Reform Act of 1995\
 , including statements regarding the capabilities and benefits of using RN
 A profiling in the drug discovery process\, results that may be implied fr
 om prior results\, the goals of HTG transcriptome-informed drug discovery 
 approach and the ability to achieve those goals\, and the design and poten
 tial benefits of HTG’s RNA platform technologies. Words such as “belie
 ves\,” “plans\,” “can\,” “expects\,” “intends\,” “will
 \,” “goal\,” “potential” and similar expressions are intended to
  identify forward-looking statements\, although not all forward-looking st
 atements necessarily contain these identifying words. These forward-lookin
 g statements are based upon management’s current expectations\, are subj
 ect to known and unknown risks\, and involve assumptions that may never ma
 terialize or may prove to be incorrect. Actual results and the timing of e
 vents could differ materially from those anticipated in such forward-looki
 ng statements as a result of various risks and uncertainties\, including\,
  without limitation\, risks associated with drug discovery and development
 \; past results may not be indicative of future results\; the risk that ou
 r RNA platform and medicinal chemistry technologies may not provide the be
 nefits that we expect\; risks associated with our ability to develop and c
 ommercialize our products\; the risk that our products and services may no
 t be adopted by biopharmaceutical companies or other customers as anticipa
 ted\, or at all\; our ability to manufacture our products to meet demand\;
  competition in our industry\; additional capital and credit availability\
 ; our ability to attract and retain qualified personnel\; risks associated
  with the impact of the COVID-19 pandemic on us and our customers\; and pr
 oduct liability claims. These and other factors are described in greater d
 etail in our filings with the Securities and Exchange Commission (SEC)\, 
 including under the “Risk Factors” heading of our Quarterly Report on 
 Form 10-Q for the quarter ended September 30\, 2022\, as filed with the 
 SEC on November 10\, 2022. All forward-looking statements contained in 
 this press release speak only as of the date on which they were made\, and
  we undertake no obligation to update such statements to reflect events th
 at occur or circumstances that exist after the date on which they were mad
 e\n\nInvestor Contact:                           \n\nAshley 
 Robinson                      \nLifeSci Advisors  
                              \nPhone: (617) 4
 30-7577                      \nEmail: arr@lifesciadv
 isors.com
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