Arizona Life Science Innovations in the Spotlight

The AZAdvances Public Information Campaign  shares stories of health solutions that are being discovered, developed, and delivered in Arizona.  The  initiative is led by AZBio in partnership with the Opportunity Through Entrepreneurship Foundation (OTEF). Working together, AZBio and OTEF are building  AZAdvances to help Arizona healthcare innovators move these innovations forward faster. 

Learn more at

Addressing the "Who Knew" Effect.

Arizona life science innovators are working to discover, develop, and deliver life saving and life changing innovations.

In 2021, AZBio is pleased to partner with ABC15 and CW61 to share quick Sonoran Living Health Innovation Spotlights during the morning and evening news hours along with longer segments on Sonoran Living periodically during 2021 to help our community learn more about the work of Arizona's healthcare innovators.

Each segment touches on a public health challenge or opportunity and spotlights an Arizona life science company's work to create a solution.

You can view all spotlights below or on the ABC15 Landing Page.

Sonoran Living Health Innovation Spotlights and Sonoran Living segments are paid for by AZBio.

Innovation Quick Links


People in Arizona are rolling up their sleeves and getting a shot in the arm. COVID-19 vaccines are a hot topic in Arizona.  How do we know that they are safe?  Would you encourage someone you love to get one?  

Questions about vaccines are natural and people need to have access to FACTS. A great science based resource is

Vaccines are an important part of our health tool kit. Not just for COVID but for a wide range of preventable diseases.  Now is the time to be sure that all of us are up-to-date on ALL of our vaccinations. 

CDC recommended vaccination schedules for children and adults

Vaccine Innovation

Innovators in Arizona are hard at work exploring how we can create new vaccines for a wide range of diseases.  One example is Calviri, led by Dr. Stephen Johnston with technology developed at the ASU Biodesign Institute. Calviri is developing a cancer vaccine.  They are starting with dogs and if successful, people may be next.  

Calviri’s mission is to provide affordable products worldwide that will end deaths from cancer by combining a unique, highly immunogenic source of neoantigens with a peptide array platform. On our course to eradicate cancer we will develop new diagnostic and therapeutic products, and then preventative vaccines that will stop cancer from starting.

Heart Disease

According to the CDC, Heart disease is the #1 cause of death worldwide for both men and women. The term “heart disease” refers to several types of heart conditions. The most common type of heart disease in the United States is coronary artery disease (CAD), which affects the blood flow to the heart. Decreased blood flow can cause a heart attack.

Learn more about Heart Disease at and at the American Heart Association.

When we think about heart disease, we often think of heart attacks, but there are many forms of heart disease and many causes. One of the most challenging is when both sides of the heart are no longer able to pump enough of blood. This is called end-stage Bi-Ventricular Heart Failure. When this occurs, the patient may need a heart transplant. But, they may not be strong enough for the surgery OR a donor heart may not be available in time.

SynCardia temporary Total Artificial Heart

SynCardia Systems in Tucson is the sole manufacturer of the only FDA-approved total artificial heart. This FDA cleared device is currently used as a bridge to transplant. The device has two main components, the TAH which is inside the patient and an external pump. As the blood flow improves, the patient can get stronger and be better prepared for when a donor heart becomes available. Patients from 8 to 80 have received a total artificial heart. The team at SynCardia recently celebrated the 2,000th patient that received this life saving technology.

SynCardia was founded in 2001 by renowned cardiothoracic surgeon Jack G. Copeland, MD; biomedical engineer Richard G. Smith, MSEE, CCE; and interventional cardiologist Marvin J. Slepian, MD.  In clinical use for more than 35 years, the SynCardia temporary Total Artificial Heart (TAH) is the most widely used and extensively studied total artificial heart in the world.

To learn more about  SynCardia


TRIF is a Smart Investment

Innovation at Arizona's Public Universities

For 20 years, every person who pays sales tax in Arizona has been investing in life saving and life changing research efforts and may not even know it. The Technology and Research Initiative Fund or TRIF for short was created in 2000 as part of Prop. 301 which added six tenths of 1 percent to the state sales tax to fund K-12 education, workforce development and a small fraction for research at our three state universities.

Those fractions added up. Thanks to TRIF, Arizona’s universities are home to world class researchers who work to explore new ways to keep us healthy and help us when we are sick. AND – during the COVID-19 pandemic, have answered the call to help us all by expanding our testing capacity, providing important health data, and more.

According to a study by the Milken Institute, commissioned by the Flinn Foundation

“the continued existence of this fund, and the commitment to research and technology it represents,  is an essential component of Arizona’s innovation economy.”

Twenty years of TRIF supported research has helped to build up Arizona’s research infrastructure and our talent base.  TRIF researchers explore big questions that impact our daily lives. 

Learn more about TRIF

Health Innovations for Babies & Children

When it comes to treatments and cures, babies and children need and deserve a special innovation focus.

One example is INC - the International Neonate Consortium led by the Critical Path Institute in Tucson. Launched on May 19, 2015, INC is C-Path’s ninth consortium – a global collaboration formed to forge a predictable regulatory path for evaluating the safety and effectiveness of therapies for neonates. “By uniting stakeholders from research institutions, drug developers, regulatory agencies, patient advocacy and other organizations,” said Janet Woodcock, Director of the U.S. Food and Drug Administration’s Center for Drug Evaluation and Research (FDA/CDER), “INC can develop practical tools that can be incorporated into clinical trials for neonates, which will then lead to more successful, efficient trials and provide this population with better treatments.”

Learn more about the International Neonatal Consortium (INC)


Shining a light on babies

Innovations in Neonatal Jaundice

Neonatal Jaundice is a common and usually harmless condition in newborn babies that causes yellowing of the skin and the whites of the eyes. In mild cases this usually goes away after 1 or 2 weeks. But sometimes a baby needs more help in the form of a medical treatment called phototherapy or light therapy.

The team at Neolight, a medical device company in Scottsdale Arizona, created Skylife to help babies with jaundice. Unlike larger systems that can only be used in a clinical or hospital setting and often result in parents and their baby being separated during the precious early days of life, Skylife is small, portable, and can even be used in a home setting allowing Parents and Baby the opportunity to stay together and bond.   

Learn more about Neolight


Developing Cancer Cures

Developing Cancer Cures

The more we learn about Cancer, the more complicated it gets.  There are more than 100 different types of cancer. Plus, each patient is unique and additional genomic changes can occur as cancer cells evolve.  When you factor all this in, the number of possible combinations is larger than the number of stars in the universe.

The talented team at Systems Oncology in Scottsdale is using Artificial Intelligence or AI for short to translate this massively complex scientific data into useful biological insights and novel cancer therapies with unprecedented speed, scale, and precision.

Learn more about Industry Investments in Cancer Drug Development


Systems Oncology, Inc.

Systems Oncology is developing a new class of multimodal RNA therapeutics that can simultaneously silence numerous disease targets with a single RNA molecule to improve outcomes and combat emerging drug resistance. 

The company's Arromer platform is used to digitally engineer and rapidly produce self-delivering therapeutics which target specific tissues with unprecedented precision and accuracy. Systems Oncology is  focused on building a pipeline of products in oncology, yet their multimodal RNA platform can be harnessed to transform outcomes for any complex polygenic disease.

Learn more about Systems Oncology


Colon Cancer Awareness

March is Colon Cancer Awareness Month but being proactive and health aware is important every month.  

Colorectal cancer is the third most common cancer in the US, and the second leading cause of cancer death. It affects men and women of all racial and ethnic groups, and is most often found in people 50 years or older. However incidence in those younger than 50 is on the rise. This disease takes the lives of more than 50,000 people every year. Colorectal cancer is also a highly preventable disease with screening.

Learn more about Colorectal Cancer

Saving Lives with Colorectal Cancer Screening

Colorectal Cancer screening is now easier than ever before.  From at home screening tests to blood tests, colon cancer screenings save lives. Here in Arizona, Beacon Biomedical's laboratory developed test (LDT) solutions help primary care providers screen their patients for the presence of undiagnosed cancer to improve their chances of survivability. BeScreened™–CRC , offers a simple blood-based solution to patients who are unwilling or unable to use traditional colorectal cancer screening methods. In 2016, Beacon Biomedical received the AZBio Fast Lane Award for their work in developing the BeScreened-CRC test.

Learn more about Beacon Biomedical

Sun Safety & Skin Cancer Awareness

May is Skin Cancer Awareness Month. Here in Arizona protecting your skin is important every day of the year.  

According to the University of Arizona Cancer, skin cancer is the most common form of cancer in the United States. It is estimated that more than 3.5 million new cases are diagnosed each year — more than all other cancers combined. One in five Americans will get skin cancer in their lifetimes. Skin cancers can affect your appearance as well as your health. Protecting your skin with sunscreen, wearing hats and protective clothing, and staying out of the sun at peak times is sun smart.

You also need to be vigilant. The best way to find skin cancer, before it becomes a serious problem, is by checking your skin regularly. Most of the brownish spots on your skin – freckles, moles, and birthmarks – are normal, but some may be skin cancers. It is important to look for changes in these spots or the appearance of new spots when checking your skin.

Learn more about how to be sun safe!

In the second video, listen to how experts in the field of dermatology utilize the DecisionDx-Melanoma test to better characterize individual risk of recurrence and metastasis in their melanoma patients.

Learn more about Castle Biosciences, Inc. 


Arizonans have been pioneering in telemedicine for decades. At our universities, in our innovative companies, and across our healthcare systems Arizona is home to leaders in using telehealth tools to make life better. These technologies are making healthcare more accessible and often more affordable too.

GlobalMed is a virtual health technology solutions leader that empowers providers to connect with patients and deliver the health services and medical expertise they need —whenever, wherever. Secure technologies support evidence-based care across specialties and acuity levels, driving efficient and expanded access to healthcare. With over 40 million teleconsults delivered in nearly 60 countries and specializing in both federal and commercial spaces, their advanced telehealth solutions are used worldwide from the VA and DoD to rural American hospitals and villages in Africa. Founded in 2002 by a Marine Corps Reserve Veteran still serving as CEO.

Learn more about GlobalMed

Pain Management

Pain is our body’s way of telling us that something is wrong or needs attention. Sometimes it may make us uncomfortable, for some people it can be debilitating.  Pain medicines designed to address high pain levels, like opioids, serve a purpose in specific cases.   They also can lead to severe or life-threatening consequences when not used correctly.

Learn more about the CDC's Rx Awareness campaign

New options to treat acute and chronic pain.

Regenesis Biomedical, an Arizona-based medical device company, has developed Provant Therapy which treats the pain site using pulsed electromagnetic energy that creates an energy field set to specific parameters, shown to reduce pain and inflammation. This FDA cleared device is providing doctors and patients with new options to treat acute and chronic pain.

Learn more about Regenesis Biomedical

Important Information for Patients

This website  and this web page are designed to spotlight Arizona-based healthcare innovations and innovators. The Arizona Bioindustry Association, Inc. (AZBio), our AZAdvances team, and our partners are not providing medical advice.  If you have a personal health related question, contact your healthcare professional.