FDA Issues ‘Letter of Support’ Encouraging Use of Synuclein-based Biomarker, αSyn-SAA, in Clinical Trials in Parkinson’s and Related Diseases

  • U.S. regulatory agency recognizes potential of alpha-synuclein seed amplification assay (αSyn-SAA) to accelerate clear outcomes in drugmakers’ trials
  • Letter is latest milestone in the journey of the biomarker, discovered in 2023, to transform drug development focused on synuclein pathology — a biological hallmark of Parkinson’s, Dementia with Lewy Bodies and related neurodegenerative conditions
  • FDA notes critical role of the Parkinson’s Progression Markers Initiative in generating and validating data and studies that made this landmark step forward possible

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Applications Open for ABRC Investigator Grants

The Arizona Biomedical Research Centre (ABRC) of the Arizona Department of Health Services is soliciting grant proposals for RFGA2024-022 Arizona Investigator Grant (AZ IG) or New Investigator Awards (NIA).
This is a two-phased application process. Approximately $10,5000,000 is available for biomedical grant projects over a period of three (3) years. 

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C-Path Awarded $1.5 Million Grant from Ara Parseghian Medical Research Fund at Notre Dame to Enhance Collaboration in Niemann-Pick Disease Research and Drug Development

TUCSON, Ariz., August 22, 2024 — Critical Path Institute (C-Path) is thrilled to announce its Critical Path for Lysosomal Diseases (CPLD) Consortium has been awarded a grant from the Ara Parseghian Medical Research Fund (APMRF) at the University of Notre Dame.Continue reading

Calviri Named Arizona Bioscience Company of the Year

Calviri, a Phoenix, Arizona based company with a mission to end cancer worldwide and to accomplish this mission with affordable products, has been named the Arizona Bioscience Company of the Year and will be celebrated at the 20th annual AZBio Awards on September 18, 2024 at the Phoenix Convention Center.

Calviri was formed in 2017 to end cancer. The  team was convinced this could be done as they had discovered a previously unappreciated, yet fundamental, molecular characteristic of all tumors that distinguishes them from healthy host cells.  Calviri also invented chip technologies that would leverage their discovery to uniquely battle cancer. After years of research and many patents, Calviri is now developing multi-cancer tests to accurately detect stage 1 disease, which can be treated with its early-stage therapeutic vaccines. Calviri’s research has also shown them the path to the seeming impossible: a preventative cancer vaccine. All rooted in the power of Calviri’s molecular discoveries and semiconductor inventions, the company is now ready to globally provide diagnostics and vaccines that will end cancer. Full stop.

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